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curcumol from plant roots to cancer roots

curcumol from plant roots to cancer roots

Curcumol: From Plant Roots to Cancer Roots

Jun 04, 2019  2. Curcumol and its natural sources. Curcumol, a bioactive sesquiterpenoid, has been isolated from numerous plants of family Zingiberaceae. These plants are mostly found in Southeast Asia, China, Indonesia, India, Peru, and West Indies 19. Curcuma, the most important genus of the family Zingiberaceae, encompasses approximately 100 species. Curcumol has been isolated from C. longa

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Curcumol: From Plant Roots to Cancer Roots

Curcumol: From Plant Roots to Cancer Roots Int J Biol Sci. 2019 Jun 4;15(8):1600-1609. doi: 10.7150/ijbs.34716. eCollection 2019. Authors Wei Wei 1 , Azhar Rasul 2 3 , Ayesha Sadiqa 3 , Iqra Sarfraz 3 , Ghulam Hussain 4 , Bushra Nageen 3 , Xintong Liu 1 ,

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(PDF) Curcumol: From Plant Roots to Cancer Roots

Curcumol: From Plant Roots to Cancer Roots. Wei Wei 1, Azhar Rasul 2,3, Ayesha Sadiqa 3, Iqra Sarfraz 3, Ghulam Hussain 4, Bushra Nageen 3, Xintong Liu 1,

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Therapeutic Effects of Curcumol in Several Diseases; An ...

Curcumae Rhizoma, also known as Ezhu is a traditional Chinese medicine that has been used for many centuries against several diseases. The rhizome of the plant is composed of curcuminoids (curcumin, demethoxycurcumin, and bisdemethoxycurcumin), and essential volatile oils including curcumol, curdione, and germacrone.

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Curcumol induces cell cycle arrest in colon cancer cells ...

Jul 04, 2017  Curcumol is one of the guaiane-type sesquiterpenoid hemiketal isolated from medicine plant Curcuma kwangsiensis S. G. Lee C. F. Liang, which has been reported possesses anti-cancer effects. Our previous study found that the most contribution to inhibit nasopharyngeal carcinoma cell growth was curcumol.

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Curcumol: de las raíces de las plantas a las raíces del ...

Curcumol: From Plant Roots to Cancer Roots Wei Wei , 1 Azhar Rasul , 2,3 Ayesha Sadiqa , 3 Iqra Sarfraz , 3 Ghulam Hussain , 4 Bushra Nageen , 3 Xintong Liu , 1 Nobumoto Watanabe , 5 Zeliha Selamoglu , 6 Muhammad Ali , 7 Xiaomeng Li , 2, and Jiang Li 1,

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Curcumol inhibits KLF5-dependent angiogenesis by blocking ...

Jan 01, 2021  It is the common preliminary stage for various chronic liver diseases to transform into some forms of liver cancer . It is well known that the activation of hepatic stellate cells (HSCs) is a key event in the occurrence of liver fibrosis. ... Curcumol: from plant roots to cancer roots. Int. J. Biol. Sci., 15 (2019), pp. 1600-1609. CrossRef View ...

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Curcumol Ameliorates Lung Inflammation and Airway ...

Jun 21, 2021  For example, curcumol could induce growth inhibition and apoptosis of non-small cell lung cancer cells;13 Peng et al found that the effect of curcumol on epigenetic regulation is realized by modulating DNA methyltransferase and histone deacetylase;14 the regulatory effects of curcumol on pulmonary fibrosis, oxidative stress, and cancer cell ...

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Curcumol: From Plant Roots to Cancer Roots [Abstract]

Curcumol: From Plant Roots to Cancer Roots . Wei Wei 1, Azhar Rasul 2,3, Ayesha Sadiqa 3, Iqra Sarfraz 3, Ghulam Hussain 4, Bushra Nageen 3, Xintong Liu 1, Nobumoto Watanabe 5, Zeliha Selamoglu 6, Muhammad Ali 7, Xiaomeng Li 2 , Jiang Li 1 . 1. Dental Hospital, Jilin

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Therapeutic Effects of Curcumol in Several Diseases; An ...

Curcumae Rhizoma, also known as Ezhu is a traditional Chinese medicine that has been used for many centuries against several diseases. The rhizome of the plant is composed of curcuminoids (curcumin, demethoxycurcumin, and bisdemethoxycurcumin), and essential volatile oils including curcumol, curdione, and germacrone.

get price

Curcumol induces cell cycle arrest in colon cancer cells ...

Jul 04, 2017  Curcumol is one of the guaiane-type sesquiterpenoid hemiketal isolated from medicine plant Curcuma kwangsiensis S. G. Lee C. F. Liang, which has been reported possesses anti-cancer effects. Our previous study found that the most contribution to inhibit nasopharyngeal carcinoma cell growth was curcumol.

get price

Curcumol inhibits KLF5-dependent angiogenesis by blocking ...

Jan 01, 2021  It is the common preliminary stage for various chronic liver diseases to transform into some forms of liver cancer . It is well known that the activation of hepatic stellate cells (HSCs) is a key event in the occurrence of liver fibrosis. ... Curcumol: from plant roots to cancer roots. Int. J. Biol. Sci., 15 (2019), pp. 1600-1609. CrossRef View ...

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Pulling Cancer’s Roots - Vanderbilt-Ingram Cancer Center

Jul 11, 2008  Pulling Cancer’s Roots. Every gardener knows that to truly eliminate a weed, you have to pull out the root. Nip the weed off at the surface only, and in time it will grow back. Such might also be the case with cancer – treatments aimed at shrinking tumors may be leaving behind the “roots,” a core of cells with the unique capacity to ...

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One-flowered Cancer Root

One flowered cancer root — also called one-flowered broomrape — is a native annual found from Vancouver Island and Southern British Columbia south to California, east to Florida and Newfoundland. This species is often found in damp woods and thickets, and open places from lowlands to moderate elevations in mountains.

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Top 20 Anti-Cancer Herbs and Plants - NaturalON

A plant based diet can help protect you from cancer as plants are rich in antioxidant and anti-inflammatory compounds, both of which are powerful cancer fighters. 1. Burdock Root. Burdock root (arctium lappa) is native to northern Asia and Europe. Historical texts described burdock root as a blood purifier. Ancient Chinese physicians would ...

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Curcumol ameliorates lung inflammation and airway ...

Figure 1 Curcumol attenuated AHR, AR, and pulmonary inflammation in chronic asthmatic mice. (A) The chemical structure of curcumol.(B) Experimental layout to develop a mice model of chronic asthma.(C) Airway resistance of the mice was detected by the forced oscillation technique.(D) Airway tissues of the mice were stained by hematoxylin-eosin to detect AR in the mice.

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Narjatamolide, an Unusual Homoguaiane Sesquiterpene ...

Narjatamolide (1), an unusual homoguaiane sesquiterpene lactone, was isolated from the roots and rhizomes of Nardostachys jatamansi DC. It represents the new carbon skeleton of a homoguaiane ...

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Product Data Sheet

Curcumol is a potent inducer of apoptosis in numerous cancer cells via targeting key signaling pathways as MAPK/ERK, PI3K/Akt and NF-κB which are generally deregulated in several cancers[1]. In Vitro Curcumol ((-)-Curcumol) is the major component extracted from root of Rhizoma Curcumae. Curcumol exerts anticancer

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Study on the Molecular Mechanism of the Herbal Couple ...

Jun 19, 2021  Background . Lung cancer has a poor prognosis and a high mortality rate, and patients may develop multidrug resistance. Sparganii Rhizoma-Curcumae Rhizoma (HCSC), the classic herbal drug combination of traditional Chinese medicine (TCM), is commonly used in treating tumors, but its molecular mechanism is still unclear. Method . We explored the possible mechanisms underlying the

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Squawroot - Pennsylvania State University

Jul 21, 2014  Squawroot ( Conopholis americana) (also called “cancer root” or “bear cone”) is a low growing, brown, scaly plant that reaches heights of one foot at maturity. It is found often in dense clusters in oak and beech forests throughout eastern North America. The plants most closely resemble brown, scaly pine cones protruding up out of the ...

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1. Introduction

Lung cancer is one of the most common malignancies worldwide; it is associated with high mortality rates, and its incidence has been increasing gradually in recent years [1].Histopathologically, lung cancer is primarily divided into small-cell lung cancer (SCLC, approximately 15% of all cases) and non-small-cell lung cancer (NSCLC, approximately 85% of all cases).

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Curcumol Overcomes TRAIL Resistance of Non‐Small Cell Lung ...

Oct 15, 2020  In conclusion, curcumol targets NQO2 and engages a ROS-driven ER stress-CHOP-DR5-dependent pathway to overcome TRAIL resistance of NSCLC (Figure 8H). 3 Discussion. Curcumol is a major sesquiterpenoid hemiketal compound isolated from the herbal medicine plant

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Curcumol attenuates epithelial-mesenchymal transition of ...

for the treatment of cancer for more than 2,000 years (12). Curcumol is extracted from the roots of the medicinal plant Rhizoma curcumae as a guaiane-type sesquiterpenoid hemiketal (13). There is a previous study on tumor treatment in clinical or scientific research focusing on TCM treatment with low toxicity and drug resistance (14). Previous ...

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Conopholis americana (American Cancer-root, Bear Corn ...

Cancer-root is an herbaceous perennial parasitic plant in the boomrape (Orobanchaceae) family. There is no evidence to prove that it can cure cancer. The genus name Conopholis comes from Latin for 'cone' and 'scale' and refers to the appearance of the stems with

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Microbial Transformation of Curcumol by Aspergillus niger

Besides curcumol, extracts from the Curcumae Rhizoma roots possess many other terpenoids such as b-ele-mene, d-elemene, germacrone, furanodiene and furanodienone with known anticancer properties.

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Squawroot - Pennsylvania State University

Jul 21, 2014  Squawroot ( Conopholis americana) (also called “cancer root” or “bear cone”) is a low growing, brown, scaly plant that reaches heights of one foot at maturity. It is found often in dense clusters in oak and beech forests throughout eastern North America. The plants most closely resemble brown, scaly pine cones protruding up out of the ...

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Cardamonin: A new player to fight cancer via multiple ...

Jun 01, 2020  Curcumol: from plant roots to cancer roots. Int. J. Biol. Sci., 15 (8) (2019), pp. 1600-1609. CrossRef View Record in Scopus Google Scholar. S. Hatziieremia, et al. The effects of cardamonin on lipopolysaccharide-induced inflammatory protein production and MAP kinase and NFkappaB signalling pathways in monocytes/macrophages.

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Cancer Root (Conopholis americana) - Illinois Wildflowers

Because Cancer Root doesn't produce chlorophyll, it is dependent on the host tree for its nourishment. Small clusters of flowering spikes often develop from the same root system. This plant spreads to new locations by reseeding itself. Cultivation: This parasitic plant is indifferent to light levels. It requires the presence of an Oak tree or ...

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Dandelion Root Can Help Cancer Patients 1MD

A further benefit reported was that the root extract also induced autophagy, which is the body's natural process of removing debris and damaged cells (such as cancer cells). In 2015, the Windsor Regional Cancer Center received approval and funding for human clinical trials to evaluate the impact of dandelion root on cancer patients.

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medicinal herbs: CANCER ROOT - Orobanche fasciculata

The root is pectoral. The chewed root has been used as a dressing on wounds and open sores. An infusion of the leaves is used as a wash on sores. Forms of the plant that are parasitic on sweet sage roots have been used as a treatment of cancer. The dried and powdered plant is inserted in the rectum as a specific treatment for haemorrhoids.

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Scientist Find Similarities Between Plant Roots and Cancer ...

May 06, 2021  Just as the roots of plants penetrate the earth, so do cancer cells in healthy tissues, revealed today a scientific study, after establishing a clear similarity.According to the journal Nature Communications, dynamics unfold with a screwed-up movement of cells in malignant tumors.. Remarkable similarities. Cancer cell specialists were able to verify that although the mechanism is

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Dandelion Root Cancer Treatment - Cancer Tutor

Jun 24, 2020  In Native American medicine, the root of the dandelion was typically chewed or boiled. People would use it to help relieve pain, ease sore throats, treat kidney disease, swelling, heartburn, and upset stomach. [2] A medical system that has been used for thousands of years to prevent, diagnose, and treat disease.

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Cúrcuma archivos - Nature95

May 03, 2021  Curcumol: From Plant Roots to Cancer Roots Wei Wei,1Azhar Rasul,2,3Ayesha Sadiqa,3Iqra Sarfraz,3Ghulam Hussain,4Bushra Nageen,3Xintong

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Curcumol Overcomes TRAIL Resistance of Non‐Small Cell Lung ...

Oct 15, 2020  In conclusion, curcumol targets NQO2 and engages a ROS-driven ER stress-CHOP-DR5-dependent pathway to overcome TRAIL resistance of NSCLC (Figure 8H). 3 Discussion. Curcumol is a major sesquiterpenoid hemiketal compound isolated from the herbal medicine plant

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Curcumol increases the sensitivity of colon cancer to 5-FU ...

Also, curcumol inhibits human cancer cells’ growth and promotes the apoptosis of various cancer cells, including cervical cancer, breast cancer, lung cancer, gastric cancer, and liver cancer (21-24). Also, curcumol has been reported to increase cancer cells’ sensitivity to adriamycin (25,26). As far as we know, there is no published ...

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[PDF] Molecular mechanisms of casticin action: an update ...

Casticin (3', 5-dihydroxy-3, 4', 6, 7-tetramethoxyflavone) is an active compound isolated from roots, stems, leaves, fruits and seeds of a variety of plants. It is well known for its pharmacological properties and has been utilized as an anti-hyperprolactinemia, anti-tumor, anti-inflammatory, neuroprotetective, analgesic and immunomodulatory agent. Recently, the anticancer activity of casticin ...

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